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              Schrödinger, Inc. Reports Second Quarter 2020 Financial Results and Business Updates

              August 10, 2020
              PDF Version

              Total revenue of $23.1 million, up 21% year-over-year

              Software revenue of $20.9 million, up 44% year-over-year

              New strategic agreements with Thermo Fisher and Viva Biotech

               Rapid progress across internal pipeline; three programs in late-stage discovery

              Conference call today, Monday, August 10, 2020 at 8:30 a.m. ET

              NEW YORK--(BUSINESS WIRE)--Aug. 10, 2020-- Schrödinger, Inc. (Nasdaq: SDGR), whose physics-based software platform enables discovery of high-quality, novel molecules for therapeutics and materials, today announced financial results for the second quarter ended June 30, 2020.

              “We made excellent progress during the second quarter across our entire business, including growing our software business, advancing our drug discovery programs, and developing new platform capabilities,” said Schrödinger CEO Ramy Farid, Ph.D. “We are excited about the opportunities across our business to continue transforming drug discovery and materials design for our customers, our collaborators, and for our own internal programs.”

              Second Quarter Financial Results

              Revenue was $23.1 million for the second quarter of 2020, an increase of 21% compared to the second quarter of 2019.

              Software revenue was $20.9 million for the second quarter of 2020, representing a 44% increase from the second quarter of 2019. Drug discovery revenue was $2.2 million for the second quarter of 2020, representing a 52% decrease from the second quarter of 2019.

              Gross profit reached $13.6 million in the second quarter of 2020, an increase of 38% over the second quarter of 2019. Software gross margin in the second quarter of 2020 was 82%, compared to 75% in the second quarter of 2019.

              Operating expenses for the second quarter of 2020 were $30.7 million, representing an increase of 29% from the second quarter of 2019.

              Other income, which includes gains on equity investments and changes in fair value of such investments, was $13.1 million in the second quarter of 2020 versus $13.2 million in the second quarter of 2019.

              Net loss, after adjusting for non-controlling interests, was $3.4 million, compared to a loss of $0.5 million in the second quarter of 2019.

              Schrödinger ended the second quarter with cash, cash equivalents, restricted cash and marketable securities of $284.5 million, a decrease of $4.2 million from the end of the first quarter of 2020.

              “We are executing on our strategy to drive growth in our software business and rapidly progress our drug discovery programs," said Schrödinger CFO Joel Lebowitz. "We continue to invest to advance the science underlying our platform and to progress our internal and collaborative drug discovery programs, which we believe will deliver long-term results.”

              Second Quarter Business Updates

              Driving growth in software business

              • $20.9 million in software revenue in the second quarter of 2020, representing 44% growth compared to the second quarter of 2019
              • Growth in software revenue was driven by the addition of new customers, expanded adoption of our software solutions by existing customers, and growth in both life sciences and materials science

              Creating value from biotech equity stakes

              • Petra Pharma was acquired by a third party, resulting in a $4.6 million cash distribution to us, as well as the potential for future earnouts. We recognized a $4.2 million gain on the distribution
              • Appreciation of shares in Morphic Holding resulted in a non-cash gain of $10.3 million
              • Anticipated non-cash gain in the third quarter, which will be based on the market value of our 422,425 shares in Relay Therapeutics, which completed its IPO in July

              Expanding platform reach

              • Drug Discovery – Entered into two strategic partnerships to expand the availability of high-resolution structures of protein complexes, which will increase the number of targets available for structure-based drug design
                • Viva Biotech - to access new x-ray crystal structures for high-value targets
                • Thermo Fisher Scientific - to leverage the capabilities of the leader in cryo-EM to obtain structures of protein complexes that may not be amenable to x-ray crystallography
              • Materials Science – Entered into three-year agreement with Gates Ventures to develop and apply atomistic simulation methods to improve battery performance

              Advancing collaborative and wholly-owned drug discovery programs

              • 12 internal and collaboration programs in late-stage discovery, including three wholly-owned programs – MALT1, CDC7 and WEE1, targeting solid tumors and hematological malignancies
              • 237 billion compounds explored computationally during the first half of 2020 across collaborative and internal programs enabling several programs to advance from program initiation to lead optimization in just months, instead of potentially years

              Advancing the underlying science

              • Significant increase in the scale and accuracy of chemical space exploration to accelerate the identification of higher quality drug candidates
              • Improved methods for determination of cryo-EM structures of protein/ligand complexes helping to expand the reach of our technology
              • Improvements to the accuracy of binding affinity predictions from FEP+ through enhanced modeling of water molecules
              • New method for calculating absolute binding affinities using FEP+ to improve hit rates in virtual screening

              “We are excited by the scientific advances and progress we have made on behalf of all our stakeholders,” said Dr. Farid. “Our leading physics-based computational platform is transforming discovery programs for life sciences and materials science with higher quality, novel molecules, and more rapidly than traditional methods.”

              Business Impact of COVID-19 Pandemic

              While we did not see material impacts to our business from the COVID-19 pandemic during the first half of 2020, we have identified certain market risks that, if they materialize, could affect the growth of our software business and the timing of our drug discovery revenues for at least the remainder of 2020. Some of our software customers may experience increasing budgetary pressures, which may cause them to delay or reduce purchases. In addition, our sales force has limited in-person interactions, and their ability to attend industry conferences and events that promote and expand knowledge of our company and platform has been hampered. Relative to our drug discovery programs, certain programs, particularly ones that are in clinical studies or preparing to enter clinical studies, could be delayed which could result in delays in achieving milestones and related revenue. While there remains uncertainty about the extent of the effect of the COVID-19 pandemic, we do not envision a long-term impact from the COVID-19 pandemic on our ability to execute on our long-term strategy.

              Webcast and Conference Call Information

              Schrödinger will host a conference call to discuss its second quarter financial results on Monday, August 10, 2020 at 8:30 AM Eastern Time. The conference call can be accessed live over the phone by dialing (833) 727-9520 (domestic) or +1 (830) 213-7697 (international) and refer to conference ID 9992538. The webcast can be accessed under "News & Events" in the investors section of Schrödinger’s website, https://ir.schrodinger.com/news-and-events/event-calendar. The archived webcast will be available on Schrödinger’s website following the event.

              About Schrödinger

              Schrödinger’s industry-leading computational platform facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions and government laboratories worldwide. Schrödinger also has wholly-owned and collaborative drug discovery programs in a broad range of therapeutic areas.

              Schrödinger is deeply committed to investing in the science and talent that drive its computational platform. Schrödinger was founded in 1990, has over 400 employees and is engaged with customers and collaborators in more than 70 countries. To learn more visit www.schrodinger.com. Follow us on LinkedIn, https://www.linkedin.com/company/schr-dinger/, and Twitter, https://twitter.com/schrodinger.

              Cautionary Note Regarding Forward-Looking Statements

              This press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995 including, but not limited to those regarding our expectations about the speed and capacity of our computational platform, our plans to continue to invest in research and our strategic plans to accelerate the growth of our software business and advance our collaborative and internal drug discovery programs, our ability to improve and advance the science underlying our platform, including through these use of new technologies, our expectations regarding the increase in the fair value of our equity stake in Relay Therapeutics, our expectations related to the use of our cash, cash equivalents, and marketable securities as well as our expectations related to the COVID-19 pandemic’s impact on our business. Statements including words such as "anticipate," "believe," "contemplate," "continue," "could," "estimate," "expect," "intend," "may," "might," "plan," "potential," "predict," "project," "should," "target," "will," "would" and statements in the future tense are forward-looking statements. These forward-looking statements reflect our current views about our plans, intentions, expectations, strategies and prospects, which are based on the information currently available to us and on assumptions we have made. Actual results may differ materially from those described in these forward-looking statements and are subject to a variety of assumptions, uncertainties, risks and factors that are beyond our control, including the demand for our software solutions, our ability to further develop our computational platform, our reliance upon third-party providers of cloud-based infrastructure to host our software solutions, our reliance upon our third-party drug discovery collaborators, the ability to retain and hire key personnel and the direct and indirect impacts of the ongoing COVID-19 pandemic on our business and other risks detailed under the caption "Risk Factors" and elsewhere in our Securities and Exchange Commission filings and reports, including our Quarterly Report on Form 10-Q for the quarterly period ended June 30, 2020 filed with the Securities and Exchange Commission on August 10, 2020, as well as future filings and reports by us. Any forward-looking statements contained in this press release speak only as of the date hereof. Except as required by law, we undertake no duty or obligation to update any forward-looking statements contained in this press release as a result of new information, future events, changes in expectations or otherwise

              Condensed Consolidated Statements of Operations (Unaudited)

               

              (in thousands, except for share and per share amounts)

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

              Three Months Ended June 30,

               

               

              Six Months Ended June 30,

               

               

               

              2020

               

               

              2019

               

               

              2020

               

               

              2019

               

              Revenues:

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

              Software products and services

               

              $

              20,900

               

               

              $

              14,482

               

               

              $

              44,712

               

               

              $

              33,087

               

              Drug discovery

               

               

              2,192

               

               

               

              4,528

               

               

               

              4,554

               

               

               

              6,664

               

              Total revenues

               

               

              23,092

               

               

               

              19,010

               

               

               

              49,266

               

               

               

              39,751

               

              Cost of revenues:

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

              Software products and services

               

               

              3,862

               

               

               

              3,671

               

               

               

              7,863

               

               

               

              6,804

               

              Drug discovery

               

               

              5,647

               

               

               

              5,488

               

               

               

              12,195

               

               

               

              10,092

               

              Total cost of revenues

               

               

              9,509

               

               

               

              9,159

               

               

               

              20,058

               

               

               

              16,896

               

              Gross profit

               

               

              13,583

               

               

               

              9,851

               

               

               

              29,208

               

               

               

              22,855

               

              Operating expenses:

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

              Research and development

               

               

              16,657

               

               

               

              9,531

               

               

               

              30,357

               

               

               

              17,969

               

              Sales and marketing

               

               

              4,362

               

               

               

              5,343

               

               

               

              9,151

               

               

               

              10,436

               

              General and administrative

               

               

              9,651

               

               

               

              8,940

               

               

               

              18,587

               

               

               

              14,026

               

              Total operating expenses

               

               

              30,670

               

               

               

              23,814

               

               

               

              58,095

               

               

               

              42,431

               

              Loss from operations

               

               

              (17,087

              )

               

               

              (13,963

              )

               

               

              (28,887

              )

               

               

              (19,576

              )

              Other income:

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

               

              Gain on equity investment

               

               

              4,156

               

               

               

              —

               

               

               

              4,156

               

               

               

              —

               

              Change in fair value

               

               

              8,359

               

               

               

              12,661

               

               

               

              5,280

               

               

               

              12,034

               

              Interest income

               

               

              570

               

               

               

              524

               

               

               

              1,269

               

               

               

              962

               

              Total other income

               

               

              13,085

               

               

               

              13,185

               

               

               

              10,705

               

               

               

              12,996

               

              Loss before income taxes

               

               

              (4,002

              )

               

               

              (778

              )

               

               

              (18,182

              )

               

               

              (6,580

              )

              Income tax expense (benefit)

               

               

              64

               

               

               

              (51

              )

               

               

              155

               

               

               

              (5

              )

              Net loss

               

               

              (4,066

              )

               

               

              (727

              )

               

               

              (18,337

              )

               

               

              (6,575

              )

              Net loss attributable to noncontrolling interest

               

               

              (716

              )

               

               

              (227

              )

               

               

              (1,161

              )

               

               

              (281

              )

              Net loss attributable to Schrödinger common and limited common stockholders

               

              $

              (3,350

              )

               

              $

              (500

              )

               

              $

              (17,176

              )

               

              $

              (6,294

              )

              Net loss per share attributable to Schrödinger common and limited common stockholders, basic and diluted:

               

              $

              (0.05

              )

               

              $

              (0.01

              )

               

              $

              (0.33

              )

               

              $

              (0.14

              )

              Weighted average shares used to compute net loss per share attributable to Schrödinger common and limited common stockholders, basic and diluted:

               

               

              63,296,366

               

               

               

              44,495,701

               

               

               

              51,981,647

               

               

               

              44,493,667

                

              Condensed Consolidated Balance Sheets (Unaudited)

               

              (in thousands, except for share and per share amounts)

               

               

               

               

               

               

               

               

               

               

              Assets

               

              June 30, 2020

               

               

              December 31, 2019

               

              Current assets:

               

               

               

               

               

               

               

               

              Cash and cash equivalents

               

              $

              110,380

               

               

              $

              25,986

               

              Restricted cash

               

               

              500

               

               

               

              500

               

              Marketable securities

               

               

              173,646

               

               

               

              59,844

               

              Accounts receivable, net of allowance for doubtful accounts of $50 and $50

               

               

              13,849

               

               

               

              18,676

               

              Unbilled and other receivables

               

               

              3,345

               

               

               

              7,062

               

              Prepaid expenses

               

               

              5,294

               

               

               

              6,468

               

              Total current assets

               

               

              307,014

               

               

               

              118,536

               

              Property and equipment, net

               

               

              5,837

               

               

               

              6,268

               

              Equity investments

               

               

              22,680

               

               

               

              15,366

               

              Right of use assets

               

               

              11,918

               

               

               

              12,762

               

              Other assets

               

               

              2,102

               

               

               

              2,338

               

              Total assets

               

              $

              349,551

               

               

              $

              155,270

               

              Liabilities, Convertible Preferred Stock, and Stockholders’ Equity (Deficit)

               

               

               

               

               

               

               

               

              Current liabilities:

               

               

               

               

               

               

               

               

              Accounts payable

               

              $

              5,523

               

               

              $

              3,524

               

              Accrued payroll, taxes, and benefits

               

               

              5,757

               

               

               

              7,034

               

              Deferred revenue

               

               

              23,138

               

               

               

              25,054

               

              Lease liabilities

               

               

              5,839

               

               

               

              5,584

               

              Other accrued liabilities

               

               

              2,791

               

               

               

              3,824

               

              Total current liabilities

               

               

              43,048

               

               

               

              45,020

               

              Deferred revenue, long-term

               

               

              1,979

               

               

               

              2,205

               

              Lease liabilities, long-term

               

               

              7,777

               

               

               

              8,888

               

              Other liabilities, long-term

               

               

              600

               

               

               

              900

               

              Total liabilities

               

               

              53,404

               

               

               

              57,013

               

              Commitments and contingencies

               

               

               

               

               

               

               

               

              Convertible preferred stock:

               

               

               

               

               

               

               

               

              Series E convertible preferred stock, $0.01 par value. Authorized zero and 77,150,132 shares; zero and 73,795,777 shares issued and outstanding at June 30, 2020 and December 31, 2019, respectively

               

               

              —

               

               

               

              109,270

               

              Series D convertible preferred stock, $0.01 par value. Authorized zero and 39,540,611 shares; zero and 39,540,611 shares issued and outstanding at June 30, 2020 and December 31, 2019, respectively

               

               

              —

               

               

               

              22,000

               

              Series C convertible preferred stock, $0.01 par value. Authorized zero and 47,242,235 shares; zero and 47,242,235 shares issued and outstanding at June 30, 2020 and December 31, 2019, respectively

               

               

              —

               

               

               

              19,844

               

              Series B convertible preferred stock, $0.01 par value. Authorized zero and 29,468,101 shares; zero and 29,468,101 shares issued and outstanding at June 30, 2020 and December 31, 2019, respectively

               

               

              —

               

               

               

              9,840

               

              Series A convertible preferred stock, $0.01 par value. Authorized zero and 134,704,785 shares; zero and 134,704,785 shares issued and outstanding at June 30, 2020 and December 31, 2019, respectively

               

               

              —

               

               

               

              30,626

               

              Total convertible preferred stock

               

               

              —

               

               

               

              191,580

               

              Stockholders' equity (deficit):

               

               

               

               

               

               

               

               

              Common stock, $0.01 par value. Authorized 500,000,000 and 425,000,000 shares; 50,139,639 and 6,121,821 shares issued and outstanding at June 30, 2020 and December 31, 2019, respectively

               

               

              501

               

               

               

              61

               

              Limited common stock, $0.01 par value. Authorized 100,000,000 and 146,199,885 shares; 13,164,193 and zero shares issued and outstanding at June 30, 2020 and December 31, 2019, respectively

               

               

              132

               

               

               

              —

               

              Additional paid-in capital

               

               

              417,032

               

               

               

              11,655

               

              Accumulated deficit

               

               

              (122,272

              )

               

               

              (105,096

              )

              Accumulated other comprehensive income

               

               

              727

               

               

               

              16

               

              Total stockholders’ equity (deficit) of Schrödinger stockholders

               

               

              296,120

               

               

               

              (93,364

              )

              Noncontrolling interest

               

               

              27

               

               

               

              41

               

              Total stockholders’ equity (deficit)

               

               

              296,147

               

               

               

              (93,323

              )

              Total liabilities, convertible preferred stock, and stockholders’ equity (deficit)

               

              $

              349,551

               

               

              $

              155,270

                

              Condensed Consolidated Statements of Cash Flows (Unaudited)

               

              (in thousands)

               

               

               

               

               

               

               

               

               

               

               

               

              Six Months Ended June 30,

               

               

               

              2020

               

               

              2019

               

              Cash flows from operating activities:

               

               

               

               

               

               

               

               

              Net loss

               

              $

              (18,337

              )

               

              $

              (6,575

              )

              Adjustments to reconcile net loss to net cash used in

               

               

               

               

               

               

               

               

              operating activities:

               

               

               

               

               

               

               

               

              Gain on equity investments

               

               

              (4,156

              )

               

               

              —

               

              Noncash revenue from equity investments

               

               

              (169

              )

               

               

              (92

              )

              Fair value adjustments

               

               

              (5,280

              )

               

               

              (12,034

              )

              Depreciation

               

               

              1,758

               

               

               

              1,793

               

              Stock-based compensation

               

               

              4,504

               

               

               

              1,051

               

              Noncash research and development expenses

               

               

              1,147

               

               

               

              227

               

              Noncash investment accretion

               

               

              (205

              )

               

               

              (212

              )

              Decrease (increase) in assets:

               

               

               

               

               

               

               

               

              Accounts receivable, net

               

               

              4,827

               

               

               

              233

               

              Unbilled and other receivables

               

               

              4,126

               

               

               

              1,044

               

              Reduction in the carrying amount of right of use assets

               

               

              2,622

               

               

               

              1,551

               

              Prepaid expenses and other assets

               

               

              (447

              )

               

               

              1,149

               

              Increase (decrease) in liabilities:

               

               

               

               

               

               

               

               

              Accounts payable

               

               

              1,999

               

               

               

              123

               

              Accrued payroll, taxes, and benefits

               

               

              (1,277

              )

               

               

              (35

              )

              Deferred revenue

               

               

              (1,973

              )

               

               

              1,779

               

              Lease liabilities

               

               

              (2,634

              )

               

               

              (1,547

              )

              Other accrued liabilities

               

               

              (1,334

              )

               

               

              2,682

               

              Net cash used in operating activities

               

               

              (14,829

              )

               

               

              (8,863

              )

              Cash flows from investing activities:

               

               

               

               

               

               

               

               

              Purchases of property and equipment

               

               

              (1,327

              )

               

               

              (1,393

              )

              Purchases of equity investments

               

               

              (2,869

              )

               

               

              —

               

              Distribution from equity investment

               

               

              4,582

               

               

               

              —

               

              Purchases of marketable securities

               

               

              (177,694

              )

               

               

              (65,504

              )

              Proceeds from sale and maturity of marketable securities

               

               

              64,808

               

               

               

              12,325

               

              Net cash used in investing activities

               

               

              (112,500

              )

               

               

              (54,572

              )

              Cash flows from financing activities:

               

               

               

               

               

               

               

               

              Issuances of common stock upon initial public offering, net

               

               

              211,491

               

               

               

              —

               

              Issuances of Series E preferred stock, net

               

               

              —

               

               

               

              29,893

               

              Issuances of common stock upon stock option exercise

               

               

              232

               

               

               

              180

               

              Contribution by noncontrolling interest

               

               

              —

               

               

               

              100

               

              Net cash provided by financing activities

               

               

              211,723

               

               

               

              30,173

               

              Net increase (decrease) in cash and cash equivalents and restricted cash

               

               

              84,394

               

               

               

              (33,262

              )

              Cash and cash equivalents and restricted cash, beginning of period

               

               

              26,486

               

               

               

              77,716

               

              Cash and cash equivalents and restricted cash, end of period

               

              $

              110,880

               

               

              $

              44,454

               

               

               

               

               

               

               

               

               

               

              Supplemental disclosure of cash flow and noncash information

               

               

               

               

               

               

               

               

              Cash paid for income taxes

               

              $

              149

               

               

              $

              43

               

              Supplemental disclosure of non-cash investing and financing activities

               

               

               

               

               

               

               

               

              Purchases of property and equipment

               

               

              —

               

               

               

              26

               

              Acquisitions of right of use assets in exchange for lease obligations

               

               

              1,778

               

               

               

              464

               

              Right of use assets recognized on adoption

               

               

              —

               

               

               

              16,475

               

              Reclass of deferred financing costs to additional paid in capital

               

               

              1,858

               

               

               

              —

               

               

              View source version on businesswire.com: https://www.businesswire.com/news/home/20200810005177/en/

              Media Contact:
              Stephanie Simon
              Ten Bridge Communications
              stephanie@tenbridgecommunications.com
              617-581-9333

              Investor Contact:
              Christina Tartaglia
              Stern IR, Inc.
              christina.tartaglia@sternir.com
              212-362-1200

              Source: Schrödinger, Inc.

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